The tests for “free” or bioavailable testosterone are considered better biomarkers. [3] X Trustworthy Source PubMed Central Journal archive from the U. S. National Institutes of Health Go to source

There are also some natural options including dietary approaches, increased exercise, and herbs such as Tribulus terrestris, Ashwagandha, Ginkgo Biloba, Maca, and Yohimbe.

Problems with sexual function. This can include erectile dysfunction, decreased desire for sexual activity, and a decrease in the number and quality of erections. Smaller testes. Emotional problems that can include depression, irritability, anxiety, problems with memory or concentration, or a lack of self-confidence. Sleep disruption. Increased fatigue or a general overall lack of energy. Body changes that include increased belly fat, decreased muscle mass along with decreased strength and endurance, decreases in cholesterol levels, softening of the bones, and decreased bone density. Swollen or tender breasts. Loss of body hair. Hot flashes.

Decreased sexual desire. Fatigue. Decreased vaginal lubrication.

Aging. Obesity and/or diabetes mellitus. Testicular injury, trauma, or infection. Radiation or chemotherapy for cancer. Chronic diseases, such as HIV/AIDS, or liver and kidney disease. Certain genetic conditions, like Klinefelter syndrome, hemochromatosis, Kallmann syndrome, Prader-Willi syndrome and others. Alcoholism. Drug abuse including heroin,marijuana, opioid or pain medication abuse. Chronic smoking. Abuse of androgens in the past.

If a man is having infertility problems If a man is having sexual problems If a boy under 15 years of age shows early signs of puberty or an older boy shows no signs of puberty If a woman develops male features, such as excessive hair growth and a deep voice If a woman has irregular menstrual periods If a man with prostate cancer is taking certain medicines If a man has osteoporosis