Any kind of over-the-counter corticosteroid cream will work.

If your poison ivy blisters are more widespread, draw a warm bath with ½ cup (90 g) of baking soda mixed in. [4] X Research source

This treatment is best for small sections of poison ivy blisters. Don’t use warm or hot water, as this won’t feel soothing on your skin irritated skin.

If you’re in a rush, try taking a short, cool shower instead.

Tea tree oil has anti-inflammatory qualities, and is great for preventing infections.

If using Benadryl, adults can take 25 to 50 mg every 4 to 6 hours. Benadryl may also help you sleep. For a non-drowsy option, take 10 mg of Claritin (loratadine) once daily. Children ages 3 to 5 can take 5mg of Claritin once per day. Another non-drowsy antihistamine is Zyrtec (cetirizine).

Unfortunately, allergy shots don’t speed up the healing process or ease any itchiness. [11] X Research source

Depending on your individual case, your doctor might prescribe an injection of triamcinolone.

If your body temperature is over 100 °F (38 °C) or your rash hasn’t cleared in 2-3 weeks, then you should schedule an emergency appointment with your doctor.

Infections tend to occur with larger outbreaks of the poison ivy rash.

Be sure to wash your clothes immediately after taking them off. Once the oil is washed off of your skin, the poison ivy is no longer contagious to other people.

Infections most often occur in popped/opened blisters.