A chancre, which is a small sore that appears near your mouth, anus, penis, or vagina. This is typically associated with swollen lymph nodes in the groin area. A rash that starts on your torso and then spreads to the rest of your body, including palms and soles which is indicative of the secondary stage of syphilis Warts around the mouth and/or genitals. Muscle aches Fever Sore throat Swollen lymph nodes

Difficulty coordinating your muscle movements Paralysis Numbness, Blindness Dementia Organ damage that can lead to death

Blood tests are used to confirm antibodies your body makes to fight the illness. [4] X Research source Testing fluid scraped from sores will show the presence of the bacteria, but can only be done when sores are present. [5] X Trustworthy Source Cleveland Clinic Educational website from one of the world’s leading hospitals Go to source Spinal fluid tests should be used when you think you may have cerebral forms of this disease. [6] X Research source

Tetracycline and doxycycline are both in the Tetracycline class of antibiotics. [9] X Research source Cephalothin is in the class: cephalosporins. [10] X Research source Erythromycin is one of the macrolides. [11] X Research source

The Jarisch-Herxheimer reaction can occur on the first day of treatment and it goes away within a few hours to a day. This reaction includes fever, chills, nausea, pain and headaches. [12] X Research source Even if treated during pregnancy, the newborn should still be treated. [13] X Trustworthy Source Mayo Clinic Educational website from one of the world’s leading hospitals Go to source

Antibiotic treatment courses work most effectively when taken according to the plan recommended by the physician or pharmacist. Taking the full course also helps prevent the development of antibiotic-resistant strains of the disease. Treatment of secondary syphilis may last an entire year but is essential to avoid the permanent disability that can be caused by tertiary syphilis.

Having syphilis once does not make you immune to the disease. You can be reinfected even after successful treatment of the disease. [15] X Trustworthy Source Centers for Disease Control and Prevention Main public health institute for the US, run by the Dept. of Health and Human Services Go to source

If you have sores on your mouth, then you should not even kiss anyone because the disease may pass through the sores. [17] X Trustworthy Source US Department of Health and Human Services Federal department responsible for improving the health and well-being of Americans Go to source

Make sure that you use dental dams or latex barriers when performing oral sex on a female partner.