Use mineral spirits for most oil-based paints. Use water for water-based paints like acrylic, watercolor, latex, and also most white glues and wood glues. If the paint is caked on, it may help to break it up with a wire brush, but keep in mind that this can damage your brush. [4] X Expert Source Patrick CoyePainting Specialist Expert Interview. 22 July 2020. Use denatured alcohol for shellac. Check the product’s label if you’re not sure what kind of paint you have. It will contain instructions for what solvent to use.
Try spinning the brush if there’s any paint remaining. [6] X Expert Source Patrick CoyePainting Specialist Expert Interview. 22 July 2020.
Be sure to dry the brush as much as possible before you store it, since storing a wet brush could lead to mold and mildew growth.
This is optional, but you can also clean with mineral spirits every few months, for a deeper clean.
